22 research outputs found
Accessibility of Health Data Representations for Older Adults: Challenges and Opportunities for Design
Health data of consumer off-the-shelf wearable devices is often conveyed to users through visual data representations and analyses. However, this is not always accessible to people with disabilities or older people due to low vision, cognitive impairments or literacy issues. Due to trade-offs between aesthetics predominance or information overload, real-time user feedback may not be conveyed easily from sensor devices through visual cues like graphs and texts. These difficulties may hinder critical data understanding. Additional auditory and tactile feedback can also provide immediate and accessible cues from these wearable devices, but it is necessary to understand existing data representation limitations initially. To avoid higher cognitive and visual overload, auditory and haptic cues can be designed to complement, replace or reinforce visual cues. In this paper, we outline the challenges in existing data representation and the necessary evidence to enhance the accessibility of health information from personal sensing devices used to monitor health parameters such as blood pressure, sleep, activity, heart rate and more. By creating innovative and inclusive user feedback, users will likely want to engage and interact with new devices and their own data
A restatement of the natural science evidence concerning catchment-based "natural” flood management in the United Kingdom
Flooding is a very costly natural hazard in Great Britain and is expected to increase further
under future climate change scenarios. Flood defences are commonly deployed to protect
communities and property from flooding, but in recent years flood management policy has
looked towards solutions that seek to mitigate flood risk at flood-prone sites through targeted
interventions throughout the catchment, sometimes using techniques which involve working
with natural processes. This paper describes a project to provide a succinct summary of the
natural science evidence base concerning the effectiveness of catchment-based “natural” flood
management in the United Kingdom. The evidence summary is designed to be read by an
informed but not technically-specialist audience. Each evidence statement is placed into one
of four categories describing the nature of the underlying information. The evidence summary
forms the appendix to this paper and an annotated bibliography is provided in the electronic
supplementary material
Effects of antiplatelet therapy on stroke risk by brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases: subgroup analyses of the RESTART randomised, open-label trial
Background
Findings from the RESTART trial suggest that starting antiplatelet therapy might reduce the risk of recurrent symptomatic intracerebral haemorrhage compared with avoiding antiplatelet therapy. Brain imaging features of intracerebral haemorrhage and cerebral small vessel diseases (such as cerebral microbleeds) are associated with greater risks of recurrent intracerebral haemorrhage. We did subgroup analyses of the RESTART trial to explore whether these brain imaging features modify the effects of antiplatelet therapy
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
Background:
Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events.
Methods:
The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627).
Findings:
Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29–146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0– 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25–1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39–1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65–1·60]; p=0·92).
Interpretation:
These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention
Effects of antiplatelet therapy after stroke due to intracerebral haemorrhage (RESTART): a randomised, open-label trial
BACKGROUND: Antiplatelet therapy reduces the risk of major vascular events for people with occlusive vascular disease, although it might increase the risk of intracranial haemorrhage. Patients surviving the commonest subtype of intracranial haemorrhage, intracerebral haemorrhage, are at risk of both haemorrhagic and occlusive vascular events, but whether antiplatelet therapy can be used safely is unclear. We aimed to estimate the relative and absolute effects of antiplatelet therapy on recurrent intracerebral haemorrhage and whether this risk might exceed any reduction of occlusive vascular events. METHODS: The REstart or STop Antithrombotics Randomised Trial (RESTART) was a prospective, randomised, open-label, blinded endpoint, parallel-group trial at 122 hospitals in the UK. We recruited adults (≥18 years) who were taking antithrombotic (antiplatelet or anticoagulant) therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage, discontinued antithrombotic therapy, and survived for 24 h. Computerised randomisation incorporating minimisation allocated participants (1:1) to start or avoid antiplatelet therapy. We followed participants for the primary outcome (recurrent symptomatic intracerebral haemorrhage) for up to 5 years. We analysed data from all randomised participants using Cox proportional hazards regression, adjusted for minimisation covariates. This trial is registered with ISRCTN (number ISRCTN71907627). FINDINGS: Between May 22, 2013, and May 31, 2018, 537 participants were recruited a median of 76 days (IQR 29-146) after intracerebral haemorrhage onset: 268 were assigned to start and 269 (one withdrew) to avoid antiplatelet therapy. Participants were followed for a median of 2·0 years (IQR [1·0- 3·0]; completeness 99·3%). 12 (4%) of 268 participants allocated to antiplatelet therapy had recurrence of intracerebral haemorrhage compared with 23 (9%) of 268 participants allocated to avoid antiplatelet therapy (adjusted hazard ratio 0·51 [95% CI 0·25-1·03]; p=0·060). 18 (7%) participants allocated to antiplatelet therapy experienced major haemorrhagic events compared with 25 (9%) participants allocated to avoid antiplatelet therapy (0·71 [0·39-1·30]; p=0·27), and 39 [15%] participants allocated to antiplatelet therapy had major occlusive vascular events compared with 38 [14%] allocated to avoid antiplatelet therapy (1·02 [0·65-1·60]; p=0·92). INTERPRETATION: These results exclude all but a very modest increase in the risk of recurrent intracerebral haemorrhage with antiplatelet therapy for patients on antithrombotic therapy for the prevention of occlusive vascular disease when they developed intracerebral haemorrhage. The risk of recurrent intracerebral haemorrhage is probably too small to exceed the established benefits of antiplatelet therapy for secondary prevention. FUNDING: British Heart Foundation
BEAST feast 2015
SpaceMaps, Manifolds and a New
Interface
Paradigm for
Spatial Music Performance
Dr. Enda Bates
[email protected]
www.endabates.net
Trinity College Dublin
BEAST FEaST
2015
University of Birmingham
30 April
?
2
May, 2015
Abstract
One of the greatest challenges facing any composer of spatial electroacoustic music is how to adapt
their work to different loudspeaker systems, their associated software interfaces
,
and
th
eir
implied
performance practice.
V
arious multi
-
channel tools exist which can be adapted for different types of
symmetrical arrays,
however,
these are
generally
entirely incompatible with the
diverse orchestras
of
loudspeakers associated with
the practice of
live
diffusion.
In addition, w
hile there have been
numerous attempts to extend or augment the one
-
fader
-
to
-
one
-
loudspeaker
approach
to diffusion
,
developing a system that can flexibly handle the complex routing of many signals in an intuit
ive and
transferrable manner
remains
a significant challenge.
Manifold
-
Interface Amplitude Panning or MIAP (pronounced ?meeap?) is one example of a
new design paradigm in which the graphical interface can be arranged
without
necessarily mirror
ing
the phys
ical layout of the array. MIAP is an expanded implementation of Meyer Sound?s SpaceMap
spatialization tool for large
-
scale spatial sound design, developed for the Max MSP environment by
Zachary Seldess
[
1
]
. While standard panner interfaces can be created u
sing MIAP,
so can
entirely
abstract
arrang
e
ments
, and these can be mapped to arbitrary numbers and
configurations of
loudspeakers or effects
.
In addition,
the
SpaceMap
can
also be used
as a flexible, transferrable
configuration and performance tool for
live diffusion
,
in which faders (or other control surfaces)
can
be mapped to arbitrary arrangements of loudspeakers, much like the concept of the m
ulti
-
point
cross fader
previously developed
by James Mooney
and David Moore for the
M2 diffusion system
[
2
]
.
The SpaceMap could therefore represent a new interface paradigm for the composition and
performance of spatial electroacoustic music which is equally applicable to both multichannel and
stereo diffusion
work, and which could greatly simplify the process of
transferring works between
different loudspeaker configurations. This paper introduces the MIAP objects for Max MSP through
the demonstration of some example diffusion strategies, the multi
-
point fader, and the transfer of
pre
-
programmed trajectories betw
een different loudspeaker configurations
Designing Auditory Cues to Enhance Spoken Mathematics for Visually Impaired Users
ABSTRACT Visual mathematic notation provides a succinct and unambiguous description of the structure of mathematical formulae in a manner that is difficult to replicate through the linear channels of synthesized speech and Braille. It is proposed that the use of auditory cues can enhance accessibility to mathematical material and reduce common ambiguities encountered through spoken mathematics. However, the use of additional complex hierarchies of non-speech sounds to represent the structure and scope of equations may be cognitively demanding to process. This can detract from the users' understanding of the mathematical content. In this paper, a new system is presented, which uses a mixture of non-speech auditory cues, modified speech (spearcons) and binaural spatialization to disambiguate the structure of mathematical formulae. A design study, involving an online survey with 56 users, was undertaken to evaluate an existing set of auditory cues and to brainstorm alternative ideas and solutions from users before implementing modified designs and conducting a separate controlled evaluation. It is proposed that by involving a wide number of users in the creative design process, intuitive auditory cues will be implemented with the potential to enhance spoken mathematics for visually impaired users